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The 7 Best Microbiome Supplements

Maintaining a healthy microbiome is crucial for overall wellbeing, as it plays a pivotal role in supporting digestive health, immune function, and overall vitality. To say that having a healthy gut is required to be healthy overall would be an understatement. In some cases, the food you eat can help keep your gut health where it needs to be. But while a balanced diet rich in fiber and fermented foods is critical to nourishing the microbiome, certain microbiome supplements can provide an extra boost if you aren’t getting enough of the good stuff in your diet.

When looking for a helping hand in setting up your microbiome for success, choosing the right microbiome supplements is essential. With so many different products out there, all claiming to help you in various ways, it can be challenging to choose the right one for your specific needs. So, what is a good supplement for bacteria in the gut? And do supplements to support the microbiome really work to optimize gut health, enhance microbial diversity, and support immune function?


There is a strong connection between probiotics and microbiome health. Why? Because probiotics are live microorganisms that provide health benefits when consumed in adequate amounts. They can help replenish beneficial bacteria in the gut, improve digestion, and strengthen the immune system.

It’s important to understand which probiotics are the best, because there are so many on the market that it can become overwhelming to choose. Look for broad-spectrum microbiome probiotics that contain various strains of bacteria, including Lactobacillus and Bifidobacterium species. Selecting a high-quality product with a guaranteed number of live organisms is essential.


Prebiotics are non-digestible fibers that serve as nourishment for beneficial gut bacteria. Together with probiotics, they can help to keep things balanced in the microbiome. They do this by promoting the growth of good bacteria (probiotics) by acting as the primary food source for these microorganisms.

Because of their crucial role in the growth and survival of the good gut bacteria that help keep you healthy, prebiotics are a vital piece of the puzzle when looking to improve the overall function and health status of your microbiome. When looking for prebiotic supplements, you’ll want to focus on certain fibers, including inulin, oligofructose, or resistant starch. These fibers are often derived from natural sources like chicory root, Jerusalem artichoke, and green bananas.

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Image by Kerd Kanno on Pixabay: What is the best way to improve my microbiome?


Postbiotics are metabolic by-products of beneficial bacteria that can provide several health benefits when it comes to your gut. They include substances like short-chain fatty acids (SCFAs) and antimicrobial peptides. Postbiotic supplements can provide the benefits of probiotics without the need for live organisms.

These supplements can support immune function, reduce inflammation, and enhance gut barrier integrity. If you want the best, however, you’ll have to find postbiotic supplements derived from fermented foods or specific strains of bacteria.

Digestive Enzymes

Digestive enzymes can support gut health by assisting in the breakdown and absorption of nutrients. When the body can absorb nutrients properly, it’s easier to stay healthy overall. However, if you’re eating a balanced diet but your body isn’t taking in all the nutrients, all those helpful vitamins and minerals will be passed out with waste, and your body will continue to lack the nutrients it needs.

This is why, for many people with unhealthy microbiomes, digestive enzymes can help. They can aid in the digestion of proteins, carbohydrates, and fats, improving nutrient availability and reducing digestive discomfort. Look for a comprehensive digestive enzyme supplement that contains a blend of proteases, lipases, and amylases to support optimal digestion.

Omega-3 Fatty Acids

Omega-3 fatty acids, particularly EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), are essential for maintaining a healthy inflammatory response in the body. These fatty acids can help reduce inflammation in the gut and support a diverse microbiome. Look for high-quality fish oil or algae-based omega-3 supplements to ensure a good source of EPA and DHA.

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Image by Bru-nO on Pixabay: What are the best gut bacteria supplements?


Polyphenols are plant compounds that possess antioxidant and anti-inflammatory properties. These are important because they can help to prevent free radical build-up, which can lead to oxidative stress. They can also help to lower unnecessary inflammation, which is the type that can lead to damage and the development of chronic diseases.

Polyphenols also help modulate the gut microbiota and support the growth of beneficial bacteria so that the good and bad bacteria within the gut remain balanced. When deciding on the perfect polyphenol, consider polyphenol-rich supplements derived from green tea extract, grape seed extract, or resveratrol.

Fiber Supplements 

Fiber is a crucial component of a healthy diet, as it promotes regular bowel movements and nourishes beneficial gut bacteria. If you struggle to consume adequate dietary fiber, consider a fiber supplement. Look for supplements that contain a mix of soluble and insoluble fiber, such as psyllium husk or glucomannan.

Optimizing gut health and supporting the microbiome is critical to enhancing overall wellbeing and immunity. While a balanced diet remains the foundation, incorporating microbiome supplements can provide additional support.

The seven best gut microbiome supplements mentioned above – probiotics, prebiotics, postbiotics, digestive enzymes, omega-3 fatty acids, polyphenols, and fiber supplements – offer a range of benefits to nourish the gut, enhance microbial diversity, and bolster immune function.

Featured image by Sprinter Lucio on Pixabay

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